論文 2023


Dehydrative Condensation of Carboxylic Acids with Amines Promoted by HBF4/MS 5A

Shuhei Ohmura, Tatsuya Ishikawa, Qianchun Huang, Takahiro Horibe, Kazuaki Ishihara*

Asian J. Org. Chem. 2024, e202300660 (4 pages).
DOI: 10.1002/ajoc.202300660 (First Published: 29 January 2024)

Tandem Isomerization/α,β-Site-Selective and Enantioselective Addition Reactions of N-(3-Butynoyl)-3,5-dimethylpyrazole Induced by Chiral π–Cu(II) Catalysts

Weiwei Guo, Masahiro Hori, Yoshihiro Ogura, Kazuki Nishimura, Kosuke Oki, Tomoyuki Ikai, Eiji Yashima, Kazuaki Ishihara*

J. Am. Chem. Soc. 2023, 145(49), 27080–27088. OPEN ACCESS

Publication Date: November 30, 2023
https://doi.org/10.1021/jacs.3c10820

▼名古屋大学プレスリリース「基質包接型キラル大環状ジリチウム(I)塩触媒の開発 〜高付加価値化合物の迅速合成で医薬品探索研究を切り拓く〜」(2023年11月8日)

[Supplementary Cover Art] Chiral Macrocyclic Catalysts for the Enantioselective Addition of Lithium Acetylides to Ketones

Kenji Yamashita, Yuji Tabata, Katsuya Yamakawa, Takuya Mochizuki, Kei Matsui, Manabu Hatano,* Kazuaki Ishihara*
J. Am. Chem. Soc. 2023, 145(48), 26238–26248.
An enantioselective addition of lithium acetylides to ketones catalyzed by macrocyclic lithium binaphtholates has been developed. The macrocyclic structure prevents aggregation, affording a monomeric and highly active catalyst that can furnish enantioenriched tertiary alcohols within 5–30 min. Moreover, the confined cavity and lipophilicity of the macrocycle confer substrate specificity. 

▼Chiral Macrocyclic Catalysts for the Enantioselective Addition of Lithium Acetylides to Ketones

Kenji Yamashita, Yuji Tabata, Katsuya Yamakawa, Takuya Mochizuki, Kei Matsui, Manabu Hatano,* Kazuaki Ishihara*
J. Am. Chem. Soc. 2023, 145(48), 26238–26248.
Published: November 4, 2023

[Commentary] Recent Progress of Iodine Catalysis Directed toward Environmentally more Benign and Sustainable Chemistry

Kazuaki Ishihara
Adv. Synth. Catal. 2023, 365(16), 2652–2652. Free Access
First published: 23 August 2023

Special Issue: Iodine in Catalysis and Organic Synthesis

Issue Editor: Kazuaki Ishihara
Adv. Synth. Catal. 2023, 365(16), 2651-2762.
Published: August 15, 2023

▼【最新のトピックス】キラルカウンターアニオンストラテジーの今 ー 不斉ラジカルカチオン反応への挑戦

大村修平、石原一彰

化学 2023, 78(9), 68–69.

▼縮合剤を用いない触媒的ペプチド合成

石原一彰 細胞, 2023, 55(9), 682–684.
ニューサイエンス社

▼オンリーワンといえるようなテーラーメイド触媒の開発を目指して ーレディメイドからテーラーメイドへのパラダイムシフト

石原一彰
ドラマティック有機合成化学 感動の瞬間100 pp. 60–61.
化学同人, 2023年7月30日発行, ISBN 978-4-7598-2336-3

Hypoiodite-Catalyzed Oxidative α-C–N Coupling of Ketones with Imides and Azoles

Mayuko Tsukahara, Muhammet Uyanik,* Kazuaki Ishihara*
Adv. Syth. Catal. 2023, 365(16), 2724–2729. Very Important Publication
First published: 17 July 2023

https://doi.org/10.1002/adsc.202300716

Highly Enantioselective Radical Cation [2 + 2] and [4 + 2] Cycloadditions by Chiral Iron(III) Photoredox Catalysis

Shuhei Ohmura, Kei Katagiri, Haruna Kato, Takahiro Horibe, Sho Miyakawa, Jun-ya Hasegawa, and Kazuaki Ishihara*
J. Am. Chem. Soc. 2023, 145(28), 15054–15060.
Publication Date: July 5, 2023

名古屋大学プレスリリース(2023年7月6日)

「キラル鉄(Ⅲ)光レドックス触媒の開発 ~SDGsと元素戦略に基づく医薬品探索研究を推進~」

日本の研究.com(2023年7月7日)

「キラル鉄(Ⅲ)光レドックス触媒の開発 ~SDGsと元素戦略に基づく医薬品探索研究を推進~」

Chem-Station (ケムステ)(2023年8月16日)
「難攻不落の不斉ラジカルカチオン反応への挑戦」

A Lewis base–silyl Lewis acid cooperative catalyst for the iodochlorination  of tetrasubsttuted alkenes

Keigo Nagami, Shuhei Ohmura,* and Kazuaki Ishihara*
Asian J. Org. Chem. 2023, 12, e20230228 (4 pages). (Special Selection: Keiji Maruoka's 70th Birthday)
DOI: 10.1002/ajoc.202300228
Publication Date: May 25, 2023.

▼触媒的エナンチオ選択的α-ハロゲン化反応に潜むハロゲン結合の影響

石原一彰

有機合成化学協会雑 2023, 81(5), 474–482.

発行日:2023/05/01, 公開日:2023/5/10

DOI: 10.5059/yukigoseikyokaishi.81.474

▼1,3-Migrative ring expansion of spiroindolenines to azepino[3,4-b]indoles

Hiroki Tanaka, Toshihiro Yasui, Muhammet Uyanik,* and Kazuaki Ishihara*
Org. Lett. 2023, 25(14), 2377–2381.
DOI: 10.1021/acs.orglett.3c00207
Publication Date: February 27, 2023.  Front Cover

Catalyst-Substrate Helical Character Matching Determines the Enantioselectivity in the Ishihara-Type Iodoarenes Catalyzed Asymmetric Kita-Dearomative Spirolactonization

Authors: Hanliang Zheng, Liu Cai, Ming Pan, Muhammet Uyanik, Kazuaki Ishihara, Xiao-Song Xue*
J. Am. Chem. Soc. 2023, 25(14), 7301–7312.
Publication Date: March 20, 2023

▼Catalytic site-, diastereo-, and enantioselective cascade iodocyclizaton of 2-geranylarenols

Yasutaka Tsuji, Kazumasa Kon, Takahiro Horibe and Kazuaki Ishihara*
Chem. Asian J. 2023, 18(7), e202300019 (Special Collection on Halogen Bonding).
DOI: 10.1002/asia.202300019
First published: 6 Feb., 2023

▼Enantioselective aromatic Claisen rearrangement of allyl 2-naphthyl ethers catalyzed by π–Cu(II) complexes

Lu Yao, Kazuki Takeda, Kaori Ando* and Kazuaki Ishihara*
Chem. Sci. 2023, 14(9), 2441–2446.
DOI: 10.1039/D2SC06771D
First published: 20 Jan., 2023

▼Bulky magnesium(II) and sodium(I) bisphenoxide catalysts for chemoselective transesterification of methyl (meth)acrylates

Xue Zhao, Manussada Ratanask, Kazumasa Kon, Jun-ya Hasegawa* and Kazuaki Ishihara*
Chem. Sci. 2023, 14(3), 566–572.
DOI: 10.1039/D2SC05413B (Publication Date: November 28, 2022)

Recruit

ポスドク及び大学院生を募集中です。

当研究室では学部生、大学院生の研究室見学を随時受け付けております。

希望者は、石原教授までメールでお問い合わせ下さい。

 

Postdoctoral and graduate students is being recruited.In our laboratory will be accepted at any time undergraduate, graduate student visits to laboratories.Those who wish, please contact us by e-mail to Professor Ishihara.

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ISHIHARA GROUP

国立大学法人 東海国立大学機構

名古屋大学

大学院工学研究科 有機・高分子化学専攻(工学部 化学生命工学科)
有機化学講座

触媒有機合成学研究グループ

〒464-8603 名古屋市千種区不老町

B2-3(611)

 

Laboratory of Catalysis in Organic Synthesis, Research Group of Molecular Chemistry, Graduate Department of Molecular and Macromolecular Chemistry, Graduate School of Engineering (Undergraduate Department of Chemistry and Biotechnology, School of Engineering), Nagoya University

Tokai National Higher Education and Research System

B2-3(611), Furo-cho, Chikusa, Nagoya 464-8603, Japan