Assist. Prof. Dr. Muhammet UYANIK

Nagoya University

Graduate School of Engineering, Department of Biotechnology

Laboratory of Catalysis in Organic Synthesis

Assistant Professor

 

Professional Societies:

The Chemical Society of Japan (CSJ)

American Chemical Society (ACS)

The Society of Synthetic Organic Chemistry, Japan (SSOCJ)

American Association for the Advancement of Science (AAAS)

The Society of Iodine Sciences, Japan (SIS)

 

muha[at]nubio.nagoya-u.ac.jp

TEL +81-52-789-3206 / FAX +81-52-789-3222


Muha Group Member (2017)

Kohei Nishioka (D2), Naoto Sahara (D1), Hirokazu Iwata (M2), Outa Katade (M1), Hiroki Tanaka (M1), Takehiro Kato (B4), Ryutaro Kondo (B4)

Alumni

Hiroaki Okamoto (2011), Ryota Fukatsu (2011), Erina Kaneko (2011), Daisuke Nakashima (2012), Dr. Takeshi Yasui (2013), Kento Ohori (2013), Dai Nagata (2014), Dr. Daisuke Suzuki (2015), Dr. Niiha Sasakura (2015), Mayuko Tsukahara (2015), Dr. Hiroki Hayashi (2016), Masahiro Mizuno (2016), Yuhei Hattori (2016), Fumio Nakashima (2016), Dr. Tatsuya Mutsuga (2017), Naoya Ukegawa (2017), Kirara Saeda (2017)

Education/Academic Experience

1981 Born in Asarcik, Samsun, Turkey

2000 Tokyo Gakuyukai International Japanese Language School, Graduated
2004 School of Engineering Nagoya University, Graduated
2006 Mr. of Eng., Department of Biotechnology, Nagoya University (Advisor: Prof. Kazuaki Ishihara)
2007 Dr. of Eng., Department of Biotechnology, Nagoya University (Advisor: Prof. Kazuaki Ishihara)
Thesis: “Development of Biomimetic Polyene Cyclization Directed towards Total Synthesis of Polycyclic Terpenoids”

2004-2007 Japanese Government (Monbukagakusho) Scholarship Student
2007 Assistant Professor, Department of Biotechnology, Nagoya University

Awards

1998 9th International Biology Olympiad, Germany, Bronze Medal

2008 Green & Sustainable Chemistry Poster Award
2008 Best Presentation Award (Academic), 88th Annual Meeting of CSJ

2009 Shionogi Award in Synthetic Organic Chemistry from SSOCJ
2009 Best Presentation Award (Academic), 89th Annual Meeting of CSJ
2010 Incentive Award for Young Scientist, Tokai Branch of SSOCJ
2011 Akazaki Prize, Nagoya University
2012 The Grand Prize of 6th Wakashachi Incentive Award, Aichi Prefectural Government
2012 The Young Scholar’s Lectureship Award, 92nd Annual Spring Meeting of CSJ

2012 The 15th Symposium on the Society of Iodine Science Poster Award

2013 The Young Scientists’ Prize (The Commendation for Science and Technology by MEXT)

2015 7th Inoue Science Research Award

2015 The 4th GSC Encouragement Award

2015 Banyu Chemist Award (BCA)

2016 Thieme Chemistry Journal Award

2017 The Chemical Society of Japan Award for Young Chemists

Professional Activities

2013–2016 Turkish Journal of Chemistry, Editorial Board

2014–2016 Journal of Synthetic Organic Chemistry, Japan Associate Member of Editorial Board

Publication

40. Chiral Hypervalent Organoiodine-Catalyzed Enantioselective Oxidative Spirolactonization of Naphthol Derivatives

Muhammet Uyanik, Takeshi Yasui, Kazuaki Ishihara

J. Org. Chem. 2017, 82, 11946–11953.

DOI: 10.1021/acs.joc.7b01941

39. alpha-Oxidation of Carbonyl Compounds

Muhammet Uyanik, Kazuaki Ishihara

In Science of Synthesis Reference Library: Catalytic Oxidation in Organic Synthesis, Kilian Muñiz (ed.), Georg Thieme-Verlag KG; 2017, pp. 635–670.

DOI; 10.1055/sos-SD-225-00320

38. 4,5-Dimethyl-2-Iodoxybenzenesulfonic Acid Catalyzed Site-Selective Oxidation of 2-Substituted Phenols to 1,2-Quinols

Muhammet Uyanik, Tatsuya Mutsuga, Kazuaki Ishihara

Angew. Chem. Int. Ed. 2017, 56, 3956–3960; Angew. Chem. 2017, 129, 4014–4018.

DOI: 10.1002/anie.201612463

37. Enantioselective Synthesis of Masked Benzoquinones Using Designer Chiral Hypervalent Organoiodine(III) Catalysis

Muhammet Uyanik, Niiha Sasakura, Masahiro Mizuno, Kazuaki Ishihara

ACS Catal. 2017, 7, 872–876.

DOI: 10.1021/acscatal.6b03380

36. Ammonium Hypoiodite-catalyzed Peroxidative Dearomatization of Phenols

Muhammet Uyanik, Kohei Nishioka, Kazuaki Ishihara

Heterocycles 2017, 95, 1132–1147.

DOI: 10.3987/COM-16-S(S)84

  • Special Issue in honor of Professor Dr. Masakatsu Shibasaki on 70th Birthday.

35. Chiral Quaternary Ammonium Hypoiodite Catalysis

Muhammet Uyanik, Kazuaki Ishihara

月刊ファインケミカル 2016, 45(12), 16–24.

特集号: ヨウ素触媒の開発最前線

34. Asymmetric Oxidative Dearomatization Reaction

Muhammet Uyanik, Kazuaki Ishihara

In Asymmetric Dearomatization Reactions, Shu-Li You (ed.), John Wiley & Sons; 2016, pp. 129–152.

DOI: 10.1002/9783527698479.ch6

33. Chiral Ammonium Hypoiodite Salt-Catalyzed Enantioselective Oxidative Cycloetherification to 2-Acyl Tetrahydrofurans

Muhammet Uyanik, Hiroki Hayashi, Hirokazu Iwata, Kazuaki Ishihara

Chem. Lett. 2016, 45, 353–355.

DOI: 10.1246/cl.160004

32. Practical Oxidative Dearomatization of Phenols with Sodium Hypochlorite Pentahydrate

Muhammet Uyanik, Niiha Sasakura, Mitsuyoshi Kuwahata, Yasukazu Ejima, Kazuaki Ishihara

Chem. Lett. 2015, 44, 381–383.

DOI: 10.1246/cl.141130

31. High-Performance Hypoiodite/Hydrogen Peroxide Catalytic System for the Oxylactonization of Aliphatic γ-Oxocarboxylic Acids

Muhammet Uyanik, Daisuke Suzuki, Mizu Watanabe, Hiroyasu Tanaka, Kikuo Furukawa, Kazuaki Ishihara

Chem. Lett. 2015, 44, 387–389.

DOI: 10.1246/cl.141110

30. Chiral Ammonium Hypoiodite-catalyzed Enantioselective Oxidative Dearomatization of 1-Naphthols Using Hydrogen Peroxide

Muhammet Uyanik, Niiha Sasakura, Erina Kaneko, Kento Ohori, Kazuaki Ishihara

Chem. Lett. 2015, 44, 179–181.

DOI: 10.1246/cl.141012

  • Editor’s Choice

29. High-turnover hypoiodite catalysis for asymmetric synthesis of tocopherols

Muhammet Uyanik, Hiroki Hayashi, Kazuaki Ishihara

Science 2014, 345, 291–294.

DOI: 10.1126/science.1254976

28. Functional Group Transformations via Carbonyl Derivatives

Muhammet Uyanik, Kazuaki Ishihara

In Comprehensive Organic Synthesis, 2nd Edition, Gary A. Molander and Paul Knochel (eds.), Vol. 6, Oxford: Elsevier; 2014, pp. 573–597.

DOI: 10.1016/B978-0-08-097742-3.00622-4

27. 2-ヨードベンゼンスルホン酸(pre-IBS)とOxoneを用いる選択的酸化反応

Muhammet Uyanik, Tatsuya Mutsuga, Kazuaki Ishihara

和光純薬時報 2013, 81(4), 5–9.

26. Hydrogen Bonding and Alcohol Effects in Asymmetric Hypervalent Iodine Catalysis: Enantioselective Oxidative Dearomatization of Phenols

Muhammet Uyanik, Takeshi Yasui, Kazuaki Ishihara

Angew. Chem. Int. Ed. 2013, 52, 9215–9218; Angew. Chem. 2013, 125, 9385–9388.

DOI: 10.1002/anie.201303559

  • Highlighted in Japanese Newspapers (Chunichi, Kagaku Kogyo Nippo).

25. Baeyer-Villiger Oxidation Using Hydrogen Peroxide

Muhammet Uyanik, Kazuaki Ishihara

ACS Catal. 2013, 3, 513–520. (Perspective)

DOI: 10.1021/cs300821u

24. Baeyer-Villiger Oxidation and Oxidative Cascade Reactions with Aqueous Hydrogen Peroxide Catalyzed by Lipophilic LiB(C6F5)4 or Ca[B(C6F5)4]2
Muhammet Uyanik, Daisuke Nakashima, Kazuaki Ishihara

Angew. Chem. Int. Ed. 2012, 51, 9093–9096; Angew. Chem. 2012, 124, 9227–9230.

DOI: 10.1002/anie.201204286

23. Conformationally-Flexible Chiral Hypervalent Organoiodine Catalysts for Enantioselective Oxidative Transformations
Muhammet Uyanik, Kazuaki Ishihara
J. Synth. Org, Chem., Jpn. 2012, 70, 1116–1122.

DOI: 10.5059/yukigoseikyokaishi.70.1116

22. デザイン型ヨウ素触媒を用いる環境調和型選択的酸化反応

Muhammet Uyanik

化学と工業 2012, 65(8), 625–626.

21. 1,2-Benziodoxol-3(1H)-one, 1-Hydroxy, 1-Oxide (First Update)

Muhammet Uyanik, Kazuaki Ishihara

Electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS), John Wiley & Sons. Published online, 14 September 2012.

DOI: 10.1002/047084289X.rn00236.pub2

20. IBS-Catalyzed Regioselective Oxidation of Phenols to 1,2-Quinones with Oxone
Muhammet Uyanik, Tatsuya Mutsuga, Kazuaki Ishihara

Molecules, 2012, 17, 8604–8616. (Special Issue: Hypervalent Compounds)

DOI: 10.3390/molecules17078604

19. 2-Iodoxy-5-Methylbenzenesulfonic Acid-Catalyzed Selective Oxidation of 4-Bromobenzyl Alcohol to 4-Bromobenzaldehyde or 4-Bromobenzoic Acid with Oxone
Muhammet Uyanik, Kazuaki Ishihara (checked by Richard Crockett, Margaret Faul)

Organic Syntheses, 2012, 89, 105–114.

DOI: 10.15227/orgsyn.089.0105

18. Catalysis with In Situ-Generated (Hypo)iodite Ions for Oxidative Coupling Reactions

Muhammet Uyanik, Kazuaki Ishihara

ChemCatChem 2012, 4, 177–185. (Concept Article)

DOI: 10.1002/cctc.201100352

  • Selected as Very Important Paper (VIP).

17. In Situ Generated (Hypo)Iodite Catalysts for the Direct alpha-Oxyacylation of Carbonyl Compounds with Carboxylic Acids
Muhammet Uyanik, Daisuke Suzuki, Takeshi Yasui, Kazuaki Ishihara

Angew. Chem. Int. Ed. 2011, 50, 5331–5334; Angew. Chem. 2011, 123, 5443–5446.

DOI: 10.1002/anie.201101522

  • Highlighted in Japanese Newspaper (Nikkan Kogyo Shinbun).
  • Highlighted in Pharmacia (by Miyamoto Kazunori, 2012, 48(3), 237).
  • Highlighted in TCI Topics.

16. In Situ-Generated Chiral Quaternary Ammonium (Hypo)iodite Catalysis for Enantioselective Oxidative Cyclisations
Muhammet Uyanik, Kazuaki Ishihara

Chimica Oggi-Chemistry Today, 2011, 29, 18–21.

15. 非共有結合相互作用を利用したキラル超原子価ヨウ素触媒の開発:北スピロラクトン化反応への応用

Muhammet Uyanik, Takeshi Yasui, Kazuaki Ishihara

和光純薬時報 2011, 79(2), 2–5.

14. Chiral Hypervalent Iodine-Catalyzed Enantioselective Oxidative Kita Spirolactonization of 1-Naphthol Derivatives and One-Pot Diastereoselective Oxidation to Epoxyspirolactones
Muhammet Uyanik, Takeshi Yasui, Kazuaki Ishihara
Tetrahedron 2010, 66, 5841–5851.

DOI: 10.1016/j.tet.2010.04.060

  • Special Issue: Hypervalent Iodine Chemistry.
  • Highlighted in Synfacts 2010, 9, 1000.
  • Recognized by Elsevier as one of their "Top-25 most cited articles" as published in Tetrahedron for 2010-2011.

13. 金属を使わない不斉酸化的カップリング触媒、無機ヨウ素酸塩へのブレークスルー

Kazuaki Ishihara, Muhammet Uyanik

化学 2010, 65(10), 12–17.

12. Quaternary Ammonium (Hypo)iodite Catalysis for Enantioselective Oxidative Cycloetherification
Muhammet Uyanik, Hiroaki Okamoto, Takeshi Yasui, Kazuaki Ishihara
Science 2010, 328, 1376–1379.

DOI: 10.1126/science.1188217

11. Enantioselective Kita Oxidative Spirolactonization Catalyzed by In Situ Generated Chiral Hypervalent Iodine(III) Species
Muhammet Uyanik, Takeshi Yasui, Kazuaki Ishihara
Angew. Chem. Int. Ed. 2010, 49, 2175–2177; Angew. Chem. 2010, 122, 2221–2223.

DOI: 10.1002/anie.200907352

  • Selected as “Hot Paper” and “Front Cover” (Issue 12).
  • Press Release from Nagoya University.
  • Highlighted in Japanese Newspapers (Chunichi, Yomiuri, Mainichi, Nikkan Kogyo, Kagaku Kogyo Nippo, Jiji Press, Kyodo Press, Yahoo News, etc.).
  • Rank in Most Accessed Articles (Mar 2010).
  • Highlighted in Synfacts 2010, 5, 602.
  • Highlighted in Journal of Synthetic Organic Chemistry, Japan 2011, 69(1), p86.
  • Chiral iodoarene pre-catalyst [(2R,2R’)-2,2’-(2-iodo-1,3-phenylene)bis(oxy)bis(N-mesitylpropanamine)] is commercially available from Wako Pure Chemical Industries, Ltd. and TCI Co., Ltd.

10. 2-Iodoxybenzenesulfonic Acid (IBS)-Catalyzed Oxidation of Alcohols

Muhammet Uyanik, Kazuaki Ishihara

Aldrichim. Acta 2010, 43(3), 83–91.

9. 2-Iodobenzenesulfonic Acid

Muhammet Uyanik, Kazuaki Ishihara

Electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS), John Wiley & Sons. Published online, 15 October 2010.

DOI: 10.1002/047084289X.rn01214.pub2

8. Bromine Catalyzed Aerobic Oxidation of Alcohols
Muhammet Uyanik, Ryota Fukatsu, Kazuaki Ishihara
Chem. Asian J. 2010, 5, 456–460.

DOI: 10.1002/asia.200900609

  • Rank in Most Accessed Articles for monthly (Feb. 2010) and for the year (2009-2010).
  • Highlighted in Journal of Synthetic Organic Chemistry, Japan 2010, 68(8), p873.

7. Hypervalent Iodine-Catalyzed Oxylactonization of Ketocarboxylic Acids to Ketolactones
Muhammet Uyanik, Takeshi Yasui, Kazuaki Ishihara
Bioorg. Med. Chem. Lett. 2009, 19, 3848–3851.

DOI: 10.1016/j.bmcl.2009.03.148

  • Special Issue: the 2009 Tetrahedron Young Investigator Award in Bioorgaic and Medicinal Chemistry in honor of its recipient Prof. C. F. Barbas.

6. IBS-Catalyzed Oxidative Rearrangement of Tertiary Allylic Alcohols to Enones with Oxone
Muhammet Uyanik, Ryota Fukatsu, Kazuaki Ishihara
Org. Lett. 2009, 11, 3470–3473.

5. Hypervalent Iodine Mediated Oxidation of Alcohols

Muhammet Uyanik, Kazuaki Ishihara

Chem. Commun. 2009, 45, 2086–2099. (Feature Article)

DOI: 10.1039/B823399C

  • Rank in ChemComm Most Cited Feature Articles 2009 Top 10.

4. 2-Iodoxybenzenesulfonic Acid as an Extremely Active Catalyst for the Selective Oxidation of Alcohols to Aldehydes, Ketones, Carboxylic Acids, and Enones with Oxone
Muhammet Uyanik, Matsujiro Akakura, Kazuaki Ishihara
J. Am. Chem. Soc. 2009, 131, 251–262.

3. Catalytic Diastereoselective Polycyclization of Homo(polyprenyl)arene Analogues Bearing Terminal Siloxyvinyl Groups
Muhammet Uyanik, Kazuaki Ishihara, Hisashi Yamamoto
Org. Lett. 2006, 8, 5649–5652.

2. Biomimetic Synthesis of Acid-Sensitive (-)- and (+)-Caparrapi Oxides, (-)- and (+)-8-Epicaparrapi Oxides, and (+)-Dysifragin Induced by Artificial Cyclases
Muhammet Uyanik, Kazuaki Ishihara, Hisashi Yamamoto
Bioorg. Med. Chem. 2005, 13, 5055–5065.

DOI: 10.1016/j.bmc.2005.04.029

  • Special Issue: Chemistry and Biology of Natural Products-Tetrahedron Prize for Creativity in Organic Chemistry 2004: K. Nakanishi.

1. Biomimetic Synthesis of Acid-Sensitive (-)-Caparrapi Oxide and (+)-8-Epicaparrapi Oxide Induced by Artificial Cyclases
Muhammet Uyanik, Hideaki Ishibashi, Kazuaki Ishihara, Hisashi Yamamoto
Org. Lett. 2005, 7, 1601–1604.

Patents

1. カルボニル化合物の製造方法 (Method for producing carbonyl compound)

Kazuaki Ishihara, Muhammet Uyanik (National University Corporation, Nagoya University)

JP Patent Pub. No. JP2008-247872(A), 2008.10.16 (Appl. No. JP2007-94377, 2007.3.30).

 

2. カルボニル化合物の製造方法およびカルボニル化合物の製造に用いる酸化促進剤 (Method for producing carbonyl compound and pro-oxidant used for production of carbonyl compound)

Kazuaki Ishihara, Muhammet Uyanik, Yukihiro Isogai, Suguru Ohara (National University Corporation, Nagoya University)

JP Patent Reg. No. JP4590514(B2), 2010.9.24 (Pub. No. JP2010-100636(A), 2010.5.6; Appl. No. JP2009-284483, 2009.12.15; Priority No. JP2007-0226843, 2007.8.31).

PCT Pub. No. WO2009-028676(A1), 2009.3.5 (Appl. No. WO2008-JP65567, 2008.8.29).

EP Patent Reg. No. EP2085373(B1), 2013.1.16 (Pub. No. EP2085373(A1), 2009.8.5; Appl. No. EP2008-828094, 2008.8.29).

US Patent Reg. No. US8394995(B2), 2013.3.12 (Pub. No. US2010-0041917(A1), 2010.2.18; Appl. No. US2009-441194, 2008.8.29).

CN Patent Reg. No. CN101541725(B), 2013.8.28 (Pub. No. CN101541725(B), 2009.9.23; Appl. No. CN2008-80000718, 2008.8.29).

 

3. 光学活性な環状エーテル化合物の製法及びそれに用いる触媒 (Method for producing optically active cyclic ether compound and catalyst used for the same)

Kazuaki Ishihara, Muhammet Uyanik (National University Corporation, Nagoya University)

JP Patent Reg. No. JP5544596(B2), 2014.5.23 (Pub. No. JP2011-57648, 2011.3.24; Appl. No. JP2009-211609, 2009.9.14).

 

4. ヨードベンゼン誘導体及びそれを用いた光学活性スピロラクトン化合物の製法 (Iodobenzene derivative and process for preparation of optically active spirolactone compound using same)

Kazuaki Ishihara, Muhammet Uyanik (National University Corporation, Nagoya University)

JP Patent Reg. No. JP5747332(B2), 2015.5.22 (Pub. No. JP WO2011-052388(A1), 2011.5.5; Appl. No. JP2011-538342, 2010.10.14; Priority No. JP2009-245275, 2009.10.26).

PCT Pub. No. WO2011-052388(A1), 2011.5.5 (Appl. No. WO2010-JP068031, 2010.10.14).

 

5. α-アシロキシカルボニル化合物の製法及び新規なα-アシロキシルカルボニル化合物 (Method for producing α-acyloxycarbonyl compound and novel α-acyloxycarbonyl compound)

Kazuaki Ishihara, Muhammet Uyanik (National University Corporation, Nagoya University; Mitsubishi Rayon Co., Ltd.)

JP Patent Reg. No. JP5770160(B2), 2015.7.3 (Pub. No. JP WO2011-108696 (A1), 2011.9.9; Appl. No. JP2012-503280, 2011.3.4; Priority No. JP2010-049003, 2010.3.5).

PCT Pub. No. WO2011-108696(A1), 2011.9.9 (Appl. No. WO2011-JP55043, 2011.3.4).

EP Patent Reg. No. EP2543658(B1), 2015.5.6 (Pub. No. EP2543658(A1), 2013.1.9; Appl. No. EP2011-0750805, 2011.3.4).

US Patent Reg. No. US8680322(B2), 2014.3.25 (Pub. No. US2012-0323014(A1), 2012.12.20; Appl. No. US2011-13581734, 2011.3.4).

CN Patent Reg. No. CN102834368(B), 2015.4.1 (Pub. No. CN102834368(A), 2012.12.19; Appl. No. CN2011-812595, 2011.3.4).

CN Patent Reg. No. CN103864608(B), 2016.3.16 (Appl. No. CN2014-178904, 2011.3.4).

TW Patent Reg. No. TWI516473(B), 2016.1.11 (Pub. No. TW201139360(A), 2011.11.16; Appl. No. TW2011-0107298, 2011.3.4).

KR Patent Pub. No. KR20130004282(A), 2013.1.9 (Appl. No. KR2012-7023122, 2011.3.4).

 

6. エステルの製法 (Method for producing esters)

Kazuaki Ishihara, Muhammet Uyanik (National University Corporation, Nagoya University)

JP Patent Reg. No. JP5920889(B2), 2016.4.22 (Pub. No. JP WO2012-060185(A1), 2012.5.10; Appl. No. JP2012-541793, 2011.10.11; Priority No. JP2010-245944, 2010.11.2).

PCT Pub. No. WO2012-060185(A1), 2012.5.10 (Appl. No. WO2011-JP73340, 2011.10.11).

EP Patent Reg. No. EP2636665(B1), 2016.6.22 (Pub. No. EP2636665(A1), 2013.9.11; Appl. No. EP2011-0837836, 2011.10.11).

US Patent Reg. No. US8853426(B2), 2014.10.7 (Pub. No. US2013-0217898(A1), 2013.8.22; Appl. No. US2011-13881544, 2011.10.11).

 

7. 窒素原子又は酸素原子を含む環構造を有する芳香族化合物の製造方法 (Method for producing aromatic compound having ring structure that includes nitrogen atom or oxygen atom)

Kazuaki Ishihara, Muhammet Uyanik (National University Corporation, Nagoya University)

JP Patent Reg. No. JP5929767(B2), 2016.5.13 (Pub. No. JP WO2012-111449(A1), 2012.8.23; Appl. No. JP2012-557880, 2012.2.2; Priority No. JP2011-033808, 2011.2.18).

PCT Pub. No. WO2012-111449(A1), 2012.8.23 (Appl. No. WO2012-JP52424, 2012.2.2).

US Patent Reg. No. US9018394(B2), 2015.4.28 (Pub. No. US2013-0338371(A1), 2013.12.19; Appl. No. US2012-13982424, 2012.2.2).

 

8. ヨードアレーン誘導体、それを用いた光学活性スピロラクトン化合物の製法及び光学活性な環化付加体の製法 (Iodoarene derivative, method for producing optically active spirolactone compound using same, and method for producing optically active cyclization adduct)

Kazuaki Ishihara, Muhammet Uyanik, Takeshi Yasui (National University Corporation, Nagoya University)

JP Patent Reg. No. JP5688647(B2), 2015.2.6 (Pub. No. JP WO2012-121248(A1), 2012.9.13; Appl. No. JP2013-503554, 2012.3.6; Priority No. JP2011-052572, 2011.3.10).

PCT Pub. No. WO2012-121248(A1), 2012.9.13 (Appl. No. WO2012-JP055679, 2012.3.6).

EP Patent Pub. No. EP2684863(A1), 2014.1.15 (Appl. No. EP2012-0754890, 2012.3.6).

US Patent Reg. No. US9000216(B2), 2015.4.7 (Pub. No. US2013-0338364(A1), 2013.12.19; Appl. No. US2012-14002574, 2012.3.6).

CN Patent Pub. No. CN103415501(A), 2013.11.27 (Appl. No. CN2012-812292, 2012.3.6).

 

9. ビアリール化合物の製造方法 (Production method for biaryl compound)

Kazuaki Ishihara, Muhammet Uyanik (National University Corporation, Nagoya University)

JP Patent Appl. No. JP2012-031223, 2012.2.16.

PCT Pub. No. WO2013-121873(A1), 2013.8.22 (Appl. No. WO2012-JP51838, 2013.1.29).

 

10. 含窒素環化合物の製造方法 (Production method for nitrogen-containing cyclic compound, and nitrogen-containing cyclic compound)

Kazuaki Ishihara, Muhammet Uyanik (National University Corporation, Nagoya University)

JP Patent Appl. No. JP2012-031224, 2012.2.16.

PCT Pub. No. WO2013-121879(A1), 2013.8.22 (Appl. No. WO2012-JP51983, 2013.1.30).

 

11. 光学活性2-アシルクロマン化合物の製法およびそれに用いる触媒前駆体 (Method for producing optically active 2-acylchroman compound and precatalyst used for the same)

Kazuaki Ishihara, Muhammet Uyanik (National University Corporation, Nagoya University)

JP Patent Reg. No. JP6004330(B2), 2016.9.16 (Pub. No. JP2014-51437(A), 2014.3.20; Appl. No. JP2012-194893, 2012.9.5).

 

12. 窒素原子を含む環構造を有する光学活性な芳香族化合物の製法 (Method for producing optically active aromatic compounds having ring structure that includes nitrogen atom)

Kazuaki Ishihara, Muhammet Uyanik, Daisuke Suzuki (National University Corporation, Nagoya University)

JP Patent Reg. No. JP6115946(B2), 2017.3.31 (Pub. No. JP2014-240365(A), 2014.12.25; Appl. No. JP2013-123423, 2013.6.12).

 

13. アリールヒドロキノン類の製法及びアリールキノン類の製法 (Method for producing aryl hydroquinone derivative and aryl quinone derivative)

Kazuaki Ishihara, Muhammet Uyanik (National University Corporation, Nagoya University)

JP Patent Pub. No. JP2015-168660, 2015.9.28 (Appl. No. JP2014-046259, 2014.3.10).

 

14. 新規なアルキルカルボニルラクトン化合物及びその製造方法 (New alkyl carbonyl lactone compounds and method for producing thereof)

Kazuaki Ishihara, Muhammet Uyanik, Kikuo Furukawa, Hiroyasu Tanaka (National University Corporation, Nagoya University; Mitsubishi Gas Co. Ltd.)

JP Patent Pub. No. JP2016-74614, 2016.5.12 (Appl. No. JP2014-204756, 2014.10.3).

External Grants

2007    JST Seeds Excavation Examination (08-477)

2010-2012 JSPS Grant-in-Aid for Young Scientists_B (20245022)

2010    JST A-STEP (AS221Z02039D)

2011-2012 JST A-STEP (AS232Z02306D)

2012-2013 JST A-STEP (AS242Z00126M)

2012-2013 JST A-STEP, East Japan Earthquake Revival Promotion (241FT0209)

2013    JSPS Challenging Exploratory Research (25620078)

2013-2014 JSPS Scientific Research on Innovative Areas: Molecular Activation (25105722)

2015-2017 JSPS Grant-in-Aid for Young Scientists_A (15H05484)

Products

Sodium 2-iodobenzenesulfonate (Pre-IBS) (CAS: 62973-39-7)

Junsei Chemical Ltd.: 80517-1615 (1g).

Potassium 2-iodobenzenesulfonate (Pre-IBS) (CAS: 62973-69-7)

Junsei Chemical Ltd.: 80516-1615 (1g).

Potassium 2-iodo-5-methylbenzenesulfonate (Pre-MIBS)(CAS: 1093215-92-9)

Sigma-Aldrich: 720011-(1g, 5g, 10g)

Junsei Chemical Ltd.: 80545-1615 (1g).

Wako Pure Chemical Industries, Ltd.: 167-25741 (100mg)163-25743 (1g), 161-25744 (5g).

(R,R)-2-Iodo-1,3-bis[1-(mesitylcarbamoyl)ethoxy]benzene (CAS: 1226896-38-3)

Wako Pure Chemical Industries, Ltd.: 095-06051 (250 mg), 091-06053 (1 g).

TCI Co. Ltd.: I0807 (200 mg).

Recruit

ポスドク及び大学院生を募集中です。

当研究室では学部生、大学院生の研究室見学を随時受け付けております。

希望者は、石原教授までメールでお問い合わせ下さい。

 

Postdoctoral and graduate students is being recruited.In our laboratory will be accepted at any time undergraduate, graduate student visits to laboratories.Those who wish, please contact us by e-mail to Professor Ishihara.

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ISHIHARA GROUP

名古屋大学

大学院工学研究科 有機・高分子化学専攻(工学部 化学生命工学科)
有機化学講座

触媒有機合成学研究グループ

〒464-8603 名古屋市千種区不老町

B2-3(611)

 

Laboratory of Catalysis in Organic Synthesis, Research Group of Molecular Chemistry, Graduate Department of Molecular and Macromolecular Chemistry, Graduate School of Engineering (Undergraduate Department of Chemistry and Biotechnology, School of Engineering), Nagoya University

B2-3(611), Furo-cho, Chikusa, Nagoya 464-8603, Japan