論文 2023

▼日本の研究.com「基質包接型キラル大環状ジリチウム(I)塩触媒の開発　〜高付加価値化合物の迅速合成で医薬品探索研究を切り拓く〜」（2023年11月9日）

▼名古屋大学プレスリリース「基質包接型キラル大環状ジリチウム(I)塩触媒の開発　〜高付加価値化合物の迅速合成で医薬品探索研究を切り拓く〜」（2023年11月8日）

▼EurekAlert "English press release about "New catalytic technique creates key component of incontinence drug in less time" (11-Jan-2024)

▼AlphaGalileo "English press release about "New catalytic technique creates key component of incontinence drug in less time" (12-Jan-2024, Top 1 Story)

▼NU Research Information "English press release about "New catalytic technique creates key component of incontinence drug in less time" (15-Jan-2024)

▼[Supplementary Cover Art] Chiral Macrocyclic Catalysts for the Enantioselective Addition of Lithium Acetylides to Ketones

Kenji Yamashita, Yuji Tabata, Katsuya Yamakawa, Takuya Mochizuki, Kei Matsui, Manabu Hatano,* Kazuaki Ishihara*

J. Am. Chem. Soc. 2023, 145(48), 26238–26248.

https://pubs.acs.org/doi/10.1021/jacs.3c08905

An enantioselective addition of lithium acetylides to ketones catalyzed by macrocyclic lithium binaphtholates has been developed. The macrocyclic structure prevents aggregation, affording a monomeric and highly active catalyst that can furnish enantioenriched tertiary alcohols within 5–30 min. Moreover, the confined cavity and lipophilicity of the macrocycle confer substrate specificity.

▼Chiral Macrocyclic Catalysts for the Enantioselective Addition of Lithium Acetylides to Ketones

Kenji Yamashita, Yuji Tabata, Katsuya Yamakawa, Takuya Mochizuki, Kei Matsui, Manabu Hatano,* Kazuaki Ishihara*

J. Am. Chem. Soc. 2023, 145(48), 26238–26248.

Published: November 4, 2023

https://pubs.acs.org/doi/10.1021/jacs.3c08905

▼[Commentary] Recent Progress of Iodine Catalysis Directed toward Environmentally more Benign and Sustainable Chemistry

Kazuaki Ishihara

Adv. Synth. Catal. 2023, 365(16), 2652–2652. Free Access

First published: 23 August 2023

▼Special Issue: Iodine in Catalysis and Organic Synthesis

Issue Editor: Kazuaki Ishihara

Adv. Synth. Catal. 2023, 365(16), 2651-2762.

Published: August 15, 2023

https://onlinelibrary.wiley.com/toc/16154169/2023/365/16

▼【最新のトピックス】キラルカウンターアニオンストラテジーの今　ー　不斉ラジカルカチオン反応への挑戦

大村修平、石原一彰

化学 2023, 78(9), 68–69.

▼縮合剤を用いない触媒的ペプチド合成

石原一彰細胞, 2023, 55(9), 682–684.
ニューサイエンス社

▼オンリーワンといえるようなテーラーメイド触媒の開発を目指して　ーレディメイドからテーラーメイドへのパラダイムシフト

石原一彰
ドラマティック有機合成化学　感動の瞬間100 pp. 60–61.
化学同人, 2023年7月30日発行, ISBN 978-4-7598-2336-3

▼Hypoiodite-Catalyzed Oxidative α-C–N Coupling of Ketones with Imides and Azoles

Mayuko Tsukahara, Muhammet Uyanik,* Kazuaki Ishihara*
Adv. Syth. Catal. 2023, 365(16), 2724–2729. Very Important Publication
First published: 17 July 2023

https://doi.org/10.1002/adsc.202300716

▼Highly Enantioselective Radical Cation [2 + 2] and [4 + 2] Cycloadditions by Chiral Iron(III) Photoredox Catalysis

Shuhei Ohmura, Kei Katagiri, Haruna Kato, Takahiro Horibe, Sho Miyakawa, Jun-ya Hasegawa, and Kazuaki Ishihara*

J. Am. Chem. Soc. 2023, 145(28), 15054–15060.

Publication Date: July 5, 2023

https://pubs.acs.org/doi/10.1021/jacs.3c04010

名古屋大学プレスリリース（2023年7月6日）

「キラル鉄(Ⅲ)光レドックス触媒の開発～SDGsと元素戦略に基づく医薬品探索研究を推進～」

日本の研究.com（2023年7月7日）

「キラル鉄(Ⅲ)光レドックス触媒の開発～SDGsと元素戦略に基づく医薬品探索研究を推進～」

Chem-Station (ケムステ)（2023年8月16日）

「難攻不落の不斉ラジカルカチオン反応への挑戦」

▼A Lewis base–silyl Lewis acid cooperative catalyst for the iodochlorination of tetrasubsttuted alkenes

Keigo Nagami, Shuhei Ohmura,* and Kazuaki Ishihara*

Asian J. Org. Chem. 2023, 12, e20230228 (4 pages). (Special Selection: Keiji Maruoka's 70th Birthday)

DOI: 10.1002/ajoc.202300228

Publication Date: May 25, 2023.

▼触媒的エナンチオ選択的α-ハロゲン化反応に潜むハロゲン結合の影響

石原一彰

有機合成化学協会雑 2023, 81(5), 474–482.

発行日：2023/05/01, 公開日：2023/5/10

DOI: 10.5059/yukigoseikyokaishi.81.474

▼1,3-Migrative ring expansion of spiroindolenines to azepino[3,4-b]indoles

Hiroki Tanaka, Toshihiro Yasui, Muhammet Uyanik,* and Kazuaki Ishihara*

Org. Lett. 2023, 25(14), 2377–2381.

DOI: 10.1021/acs.orglett.3c00207

Publication Date: February 27, 2023. Front Cover

▼Catalyst-Substrate Helical Character Matching Determines the Enantioselectivity in the Ishihara-Type Iodoarenes Catalyzed Asymmetric Kita-Dearomative Spirolactonization

Authors: Hanliang Zheng, Liu Cai, Ming Pan, Muhammet Uyanik, Kazuaki Ishihara, Xiao-Song Xue*

J. Am. Chem. Soc. 2023, 25(14), 7301–7312.

DOI: 10.1021/jacs.2c13295

Publication Date: March 20, 2023

▼Catalytic site-, diastereo-, and enantioselective cascade iodocyclizaton of 2-geranylarenols

Yasutaka Tsuji, Kazumasa Kon, Takahiro Horibe and Kazuaki Ishihara*

Chem. Asian J. 2023, 18(7), e202300019 (Special Collection on Halogen Bonding).

DOI: 10.1002/asia.202300019

First published: 6 Feb., 2023

▼Enantioselective aromatic Claisen rearrangement of allyl 2-naphthyl ethers catalyzed by π–Cu(II) complexes

Lu Yao, Kazuki Takeda, Kaori Ando* and Kazuaki Ishihara*

Chem. Sci. 2023, 14(9), 2441–2446.

DOI: 10.1039/D2SC06771D

First published: 20 Jan., 2023

▼Bulky magnesium(II) and sodium(I) bisphenoxide catalysts for chemoselective transesterification of methyl (meth)acrylates

Xue Zhao, Manussada Ratanask, Kazumasa Kon, Jun-ya Hasegawa* and Kazuaki Ishihara*

Chem. Sci. 2023, 14(3), 566–572.

DOI: 10.1039/D2SC05413B (Publication Date: November 28, 2022)

最先端機能分子・材料合成技術ユニット Facebook Page

Recruit

ポスドク及び大学院生を募集中です。

当研究室では学部生、大学院生の研究室見学を随時受け付けております。

希望者は、石原教授までメールでお問い合わせ下さい。

Postdoctoral and graduate students is being recruited.In our laboratory will be accepted at any time undergraduate, graduate student visits to laboratories.Those who wish, please contact us by e-mail to Professor Ishihara.

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ISHIHARA GROUP

国立大学法人東海国立大学機構

名古屋大学

大学院工学研究科有機・高分子化学専攻（工学部化学生命工学科）
有機化学講座

触媒有機合成学研究グループ

〒464-8603 名古屋市千種区不老町

B2-3(611)

Laboratory of Catalysis in Organic Synthesis, Research Group of Molecular Chemistry, Graduate Department of Molecular and Macromolecular Chemistry, Graduate School of Engineering (Undergraduate Department of Chemistry and Biotechnology, School of Engineering), Nagoya University

Tokai National Higher Education and Research System

B2-3(611), Furo-cho, Chikusa, Nagoya 464-8603, Japan